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2018年

英文論文

  1. Yamaguchi S, Fujii T, Izumi Y, Fukumura Y, Han M, Yamaguchi H, Akita T, Yamashita C, Kato S, and Sekiya T: Identification and characterization of a novel adenomatous polyposis coli mutation in adult pancreatoblastoma. Oncotarget 9: 10818-10827, 2018.
  2. Ikenoue T, Terakado Y, Zhu C, Liu X, Ohsugi T, Matsubara D, Fujii T, Kakuta S, Kubo S, Shibata T, Yamaguchi K, Iwakura Y, and Furukawa Y: Establishment and analysis of a novel mouse line carrying a conditional knockin allele of a cancer-specific FBXW7 mutation. Scientific Reports 8: 2021, 2018.
  3. Mizunoe Y, Watanabe S, Sudo Y, Kobayashi M, Yasukawa H, Natori D, Negishi A, Hoshino A, Negishi A, Okita N, Komatsu M, and Higami Y: Trehalose protects against oxidative stress through the regulation of both Keap1-Nrf2 and autophagy pathways. Redox Biology 15: 115-124, 2018.
  4. Miyazaki M, Otomo R, Matsushima-Hibiya Y, Suzuki H, Nakajima A, Abe N, Tomiyama A, Ichimura K, Matsuda K, Watanabe T, Ochiya T, Nakagama H, Sakai R, and Enari M: The p53 activator overcomes resistance to ALK inhibitors by regulating p53-target selectivity in ALK-driven neuroblastomas. Cell Death Discovery 4: 56, 2018.
  5. Miyamoto S, Nagamura Y, Nakabo A, Okabe A, Yanagihara K, Fukami K, Sakai R, and Yamaguchi H: Aberrant alternative splicing of RHOA is associated with loss of its expression and activity in diffuse-type gastric carcinoma cells. Biochem. Biophys. Res. Comm. 495: 1942-1947, 2018.
  6. Yamamoto Y, Tomiyama A, Sasaki N, Yamaguchi H, Shirakihara T, Nakashima K, Kumagai K, Takeuchi S, Toyooka T, Otani N, Wada K, Narita Y, Ichimura K, Sakai R, Namba H, and Mori K: Intracellular cholesterol level regulates sensitivity of glioblastoma cells against temozolomide-induced cell death by modulation of caspase-8 activation via death receptor 5-accumulation and activation in the plasma membrane lipid raft. Biochem. Biophys. Res. Comm. 495: 1292-1299, 2018.

国際学会

 

2017年

英文論文

  1. Kobayashi M, Takeda K, Narita T, Nagai K, Okita N, Sudo Y, Miura Y, Tsumoto H, Nakagawa Y, Shimano H, and Higami Y: Mitochondrial Intermediate Peptidase is a Novel Regulator of Sirtuin-3 Activation by Caloric Restriction. FEBS letters 591: 4067-4073, 2017.
  2. Okita N, Higami Y, Fukai F, Kobayashi M, Mitarai M, Sekiya T, and Sasaki T: Modified Western blotting for insulin and other diabetes-associated peptide hormones. Scientific Reports 7: 6949, 2017.
  3. Fujii N, Narita T, Okita N, Furuta Y, Chujo Y, Sakai M, Yamada A, Takeda K, Konishi T, Sudo Y, Shimokawa I, and Higami Y: Sterol Regulatory Element-Binding Protein-1c Orchestrates Metabolic Remodeling of White Adipose Tissue by Caloric Restriction. Aging Cell 16: 508-517, 2017.
  4. Mizunoe Y, Sudo Y, Okita N, Hiraoka H, Mikami K, Narahara T, Negishi A, Yoshida M, Higashibata R, Watanabe S, Kaneko H, Natori D, Furuichi T, Kobayashi M, and Higami Y: Involvement of Lysosomal Dysfunction in Autophagosome Accumulation and Early Pathologies in Adipose Tissue of Obese Mice. Autophagy 13: 642-653, 2017.
  5. Sato H, Niimi A, Yasuhara T, Permata TBM, Hagiwara Y, Isono M, Nuryadi E, Sekine R, Oike T, Kakoti S, Yoshimoto Y, Held KD, Suzuki Y, Kono K, Miyagawa K, Nakano T, and Shibata A: DNA double-strand break repair pathway regulates PD-L1 expression in cancer cells. Nature Communications 8: 1751, 2017.
  6. Sakasai R, Isono M, Wakasugi M, Hashimoto M, Sunatani Y, Matsui T, Shibata A, Matsunaga T, and Iwabuchi K: Aquarius is required for proper CtIP expression and homologous recombination repair. Scientific Reports 7: 13808, 2017.
  7. Nakajima NI, Niimi A, Isono M, Oike T, Sato H, Nakano T, and Shibata A: Inhibition of the HDAC/Suv39/G9a pathway restores the expression of DNA damage-dependent major histocompatibility complex class I-related chain A and B in cancer cells. Oncology Reports 38: 693-702, 2017.
  8. Isono M, Niimi A, Oike T, Hagiwara Y, Sato H, Sekine R, Yoshida Y, Isobe SY, Obuse C, Nishi R, Petricci E, Nakada S, Nakano T, and Shibata A: BRCA1 Directs the Repair Pathway to Homologous Recombination by Promoting 53BP1 Dephosphorylation. Cell Reports 18: 520-532, 2017.
  9. Kobayashi D, Oike T, Shibata A, Niimi A, Kubota Y, Sakai M, Amornwhichet N, Yoshimoto Y, Hagiwara Y, Kimura Y, Hirota Y, Sato H, Isono M, Yoshida Y, Kohno T, Ohno T, and Nakano T: Mitotic catastrophe is a putative mechanism underlying the weak correlation between sensitivity to carbon ions and cisplatin. Scientific Reports 7: 40588, 2017.
  10. Yamaguchi H, Ito Y, Miura N, Nagamura Y, Nakabo A, Fukami K, Honda K, and Sakai R: Actinin-1 and actinin-4 play essential but distinct roles in invadopodia formation by carcinoma cells. Eur. J. Cell Biol. 96: 685-694, 2017.
  11. Nakashima K, Uekita T, Yano S, Kikuchi J, Nakanishi R, Sakamoto N, Fukumoto K, Nomoto A, Kawamoto K, Shibahara T, Yamaguchi H, and Sakai R: Novel small molecule inhibiting CDCP1-PKCδ pathway reduces tumor metastasis and proliferation. Cancer Sci. 108: 1049-1057, 2017.
  12. Terasaki M, Maeda H, Miyashita K, Tanaka T, Miyamoto S, and Mutoh M: A marine bio-functional lipid, fucoxanthinol, attenuates human colorectal cancer stem-like cell tumorigenicity and sphere formation. J. Clin. Biochem. Nutr. 61: 25-32, 2017.
  13. Onuma W, Asai D, Tomono S, Miyamoto S, Fujii G, Hamoya T, Nagano A, Takahashi S, Masumori S, Miyoshi N, Wakabayashi K, and Mutoh M: Anticarcinogenic Effects of Dried Citrus Peel in Colon Carcinogenesis Due to Inhibition of Oxidative Stress. Nutr. Cancer. 69: 855-861, 2017.
  14. Hamoya T, Miyamoto S, Tomono S, Fujii G, Nakanishi R, Komiya M, Tamura S, Fujimoto K, Toshima J, Wakabayashi K, and Mutoh M: Chemopreventive effects of a low-side-effect antibiotic drug, erythromycin, on mouse intestinal tumors. J. Clin. Biochem. Nutr. 60: 199-207, 2017.
  15. Miyamoto S, Komiya M, Fujii G, Hamoya T, Nakanishi R, Fujimoto K, Tamura S, Kurokawa Y, Takahashi M, Ijichi T, and Mutoh M: Preventive Effects of Heat- Killed Enterococcus faecalis Strain EC-12 on Mouse Intestinal Tumor Development. Int. J. Mol. Sci. 18: 826, 2017.
  16. Noma N, Fujii G, Miyamoto S, Komiya M, Nakanishi R, Shimura M, Tanuma SI, and Mutoh M: Impact of Acetazolamide, a Carbonic Anhydrase Inhibitor, on the Development of Intestinal Polyps in Min Mice. Int. J. Mol. Sci. 18: E851, 2017.

2016年

英文論文

  1. Fujii T, Tsunesumi S, Sagara H, Munakata M, Hisaki Y, Sekiya T, Furukawa Y, Sakamoto K, and Watanabe S: Smyd5 plays pivotal roles in both primitive and definitive hematopoiesis during zebrafish embryogenesis. Scientific Reports 6: 29157, 2016.
  2. Ikenoue T, Terakado Y, Nakagawa H, Hikiba Y, Fujii T, Matsubara D, Noguchi R, Zhu C, Yamamoto K, Kudo Y, Asaoka Y, Yamaguchi K, Ijichi H, Tateishi K, FukushimaN, Maeda S, Koike K, and Furukawa Y: A novel mouse model of intrahepatic cholangiocarcinoma induced by liver-specific Kras activation and Pten deletion. Scientific Reports 6: 23899, 2016.
  3. Kawai M, Komiyama H, Hosoya M, Okubo H, Fujii T, Yokoyama N, Sato C, Ueyama T,Okuzawa A, Goto M, Kojima Y, Takahashi M, Sugimoto K, Ishiyama S, Munakata S,Ogura D, Niwa SI, Tomiki Y, Ochiai T, and Sakamoto K: Impact of chromosome 17q deletion in the primary lesion of colorectal cancer on liver metastasis. Oncol Lett. 12: 4773-4778, 2016.

国際学会

  1. Fujii T, Tsunesumi S, Sagara H, Munakata M, Hisaki Y, Sekiya T, Furukawa Y, Sakamoto K, and Watanabe S: Expression and functional analysis of Smyd5 in zebrafish. 2016 American Society for Cell Biology Annual Meeting, San Francisco, USA, 2016.
  2. Okita N, Matsushima S, Nagai W, and Higami Y: Novel regulatory mechanism of parp1 protein mediated by mdm2 inhibitors. The 4th International Postgraduate Conference on Pharmaceutical Sciences, Chiba, Japan, 2016.

2015年

英文論文

  1. Okita N, Tsuchiya T, Fukushima M, Itakura K, Yuguchi K, Narita T, Hashizume Y, Sudo Y, Chiba T, Shimokawa I, and Higami Y: Chronological analysis of caloric restriction-induced alteration of fatty acid biosynthesis in white adipose tissue of rats. Experimental Gerontology 63: 59-66, 2015.
  2. Yashima Y, Sato S, Kawai T, Sugimoto T, Sato T, Kanda M, and Obi S: Intra-arterial 5-Fluorouracil and Interferon Therapy is Safe and Effective for Nonresectable Biliary Tract Adenocarcinoma. Hepatology international 9: 142-148, 2015.
  3. Fujii T, Saito M, Hasegawa T, Iwata T, Kuramoto H, Kubushiro K, Ohmura M, Ochiai K, Arai H, Sakamoto M, Motoyama T, and Aoki D: Performance of p16INK4a/Ki-67 immunocytochemistry for identifying CIN2+ in atypical squamous cells of undetermined significance and low-grade squamous intraepithelial lesion specimens: a Japanese Gynecologic Oncology Group study. Int J Clin Oncol 20: 134-42, 2015.
  4. Nakano S, Morimoto S, Suzuki S, Tsushima H, Yamanaka K, Sekigawa I, and Takasaki Y: Immuno-regulatory Role of IL-35 in T Cells from Patients with Rheumatoid Arthritis. Rheumatology (Oxford) 54: 1498-1506, 2015.

国際学会

  1. Matsudaira R, Tamura N , Sugisaki Y, Ito T, Minowa K, Ogasawara M, Yamaji K, Kanai Y, Yamanaka K and Takasaki Y: Study of the Production of Antinuclear Antibodies and Anti-Ds DNA Antibodies in Rheumatoid Arthritis Patients Treated with TNF Inhibitors. 2015 ACR/ARHP Annual Meeting, San Francisco, USA, 2015.
  2. Sato S: A case of radiofrequency ablation after Trans Arterial Embolization with Microsphere for hepatic metastases from ovarian cancer. 2nd Asian Conference on Tumor Ablation, Fukuoka, Japan, 2015.
  3. Sato S: Expanding the indications for radiofrequency ablation of hepatocellular carcinoma or metastatic tumor. 2015 International Symposium of Cancer Research, Taipei, Taiwan, 2015.
  4. Kawai T: The role of local ablation for liver cancer in Japan and in the future. 2015 International Symposium of Cancer Research, Taipei, Taiwan, 2015.
  5. Tomita Y, Aritomi K, Naito K, Nagahama Y, and Watari T: Treatment for the fracture of the hook of hamate using a minimum invasive technique with Acutrack mini screw. XX Federation of European societies for surgery of the hand, Milano, Italy, 2015.
  6. Sato S: Percutaneous urtrasound-guided radiofrequency ablation for extrahepatic neoplasms. 24th Conference of APASL (Asian Pacific Association for the Study of the Liver), Istanbul, Turkey, 2015.
  7. Yashima Y: ECR 2015, Vienna, Austria, 2015.

2014年

英文論文

  1. Hatachi G, Tsuchiya T, Miyazaki T, Matsumoto K, Yamasaki N, Okita N, Nagashima A, Higami Y, and Nagayasu T: Poly(ADP-ribose) Polymerase Inhibitor (PJ34) Reduces Pulmonary Ischemia-Reperfusion Injury in Rats. Transplantation 98: 618-624, 2014.
  2. Sugimoto T, Yoichi T, Suzuki K, Kawai T, Yashima Y, Sato S, Kawamoto J, and Obi S: Endoscopic Submucosal Dissection to Treat Ileal High-grade Dysplasia after Ileoanal Anastomosis for Familial Adenomatous Polyposis: Report of a case. Clinical journal of gastroenterology 7: 481-483, 2014.
  3. Takahashi E, Koshiishi H, Sakaniwa N, Okunaka T, Takei H, Hayahsi N, Takahashi M, and Ikeda N: Photodynamic therapy for multiple central type lung cancer-A case report. Jpn J Cancer Chemother 41: 2042-2043, 2014.
  4. Kikuchi R, Kikuchi Y, Tsuda H, Maekawa H, Kozaki KI, Imoto I, Tamai S, Shiotani A Iwaya K, Sakamoto M, Sekiya T, Matsubara O., The expression and clinical significance of connective tissue growth factor in advanced head and neck squamous cell cancer. Human Cell 27: 121-128, 2014.
  5. Mikami M, Y, Sakamoto M, Shimada M, Takeshima N, Fujiwara H, Matsumoto T, Kita T, and Takizawa K: Disease Committee of Uterine Cervical and Vulvar Cancer, Japanese Gynecologic Oncology Group, Surgical Principles for Managing Stage IB2, IIA2, and IIB, Uterine Cervical Cancer (Bulky Tumors) in Japan, A Survey of the Japanese Gynecologic Oncology Group. Int J Gynecol Cancer 24: 1333-1340, 2014.

国際学会

  1. Nakano S et al.: 16th ASIA Pacific League of Associations for Rheumatology Congress (APLAR 2014), Cebu City, Philippines, 2014.
  2. Suzuki S, Nakano S, Matsudaira R, et al.: Identification of a factor predicting response to tocilizumab as treatment for rheumatoid arthritis. 16th ASIA Pacific League of Associations for Rheumatology Congress (APLAR 2014), Cebu City, Philippines, 2014.
  3. Sato S: Percutaneous urtrasound-guided radiofrequency ablation for extrahepatic neoplasms. APASL Conference, Brisbane, Australia, 2014.
  4. Tomita Y, Nakajima M R, Nagahama Y, Kusunose K, Hara S, Ichihara S, and Noike K: Treatment for the intraarticular fracture of distal radius, reduction with intrafocal intramedullary pinning by fragment specific classification. 19th Federation of European Societies for Surgery of the Hand, Paris, France, 2014.